4-Bromo-2,6-difluoroaniline
CAS Number 67567-26-4
Chemistry Building Blocks, Fluorinated Building Blocks, Materials, Monomers, Non-Heterocyclic Building Blocks
A tri-halogenated aniline building block
A synthesis intermediate for azo-dyes and macromolecules in application of solar cells, OLEDs, organic semiconductors, self-assemble molecular architectures and drug release
Specifications | MSDS | Literature and Reviews
4-Bromo-2,6-difluoroaniline (CAS number 67567-26-4) is an aniline derivative with a bromine at para-position and two fluorines at ortho-positions. The multiple substituents have different chemical reactivities, making 4-bromo-2,6-difluoroaniline a versatile building block in chemical synthesis. The bromo-substituent allows Pd-catalysed coupling reaction for expanding the size of the molecule. The amine group is used as a nucleophile in a chemical reaction, or it can also be oxidised to amine oxide to synthesize conjugated azo compounds. The fluoro-substitutes adjust the energy level of the molecular orbitals while they can undergo nucleophilic aromatic substitution for designing macromolecules.
A Pd-azobenzene complex based on 4-bromo-2,6-difluoroaniline has shown photo-switching properties. It can reversibly switch to two discrete self-assembled structures. A conjugated quasiplanar triarylamines synthesized from 4-bromo-2,6-difluoroaniline is used as hole-transporting material in perovskite solar cells and OLEDs.
Multiple functional groups
For facile synthesis
Fluorinated aniline building block
For semiconductors, solar cells and OLEDs
Worldwide shipping
Quick and reliable shipping
High purity
>98% High purity
General Information
| CAS Number | 67567-26-4 |
| Chemical Formula | C6H4F2NBr |
| Full Name | 4-Bromo-2,6-difluoroaniline |
| Molecular Weight | 208.01 g/mol |
| Synonyms | 4-Bromo-2,6-difluorobenzenamine |
| Classification / Family | Fluorinated building block, Amine building block, Azo-dyes, solar cells, OLEDs, semiconductors, macromolecules |
Chemical Structure
Product Details
| Purity | 98% |
| Melting Point | Tm = 63 – 65 °C |
| Appearance | White powder |
MSDS Documentation
4-Bromo-2,6-difluoroaniline MSDS Sheet
Literature and Reviews
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Partially oxygen-bridged triphenylamines with a quasiplanar structure as a key scaffold for hole-transporting materials, A. Wakamiya et al., J. Synth. Org. Chem. Jpn., 74(11), 1128–1135(2016); DOI: 10.5059/yukigoseikyokaishi.74.1128.
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Selective release of a potent anticancer agent from a supramolecular hydrogel using green light, J. Karcher et al., RSC Adv., 11, 8546(2021); DOI: 10.1039/d0ra08893e.
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Synthesis of novel phenoxyimine ligands containing a 2,6-difluoro-4-styrylaniline, B. Liu et al., J. Chem. Res., 35(3), 151–153(2011); DOI: 10.3184/174751911X12979306434042.