3,4,5-Trifluoroaniline
CAS Number 163733-96-8
Chemistry Building Blocks, Fluorinated Building Blocks, Materials, Monomers
Fluorinated aniline building block
For synthesizing APIs and perovskites for OLEDs
Specifications | MSDS | Literature and Reviews
3,4,5-Trifluoroaniline (CAS number 163733-96-8) is an aniline building block with three fluorine atoms at 3-, 4-, and 5-positoins. 3,4,5-Trifluoroaniline is often used as an electron deficient aniline for substrate scope study in organic synthesis. Organic colour centres can be produced by 3,4,5-trifluoroaniline functionalised single wall carbon nanotubes (SWCNTs), generating distinct fluorescence bands at longer wavelengths from the emission of SWCNTs (E11). The functionalisation of SWCNTs is performed in one pot with 3,4,5-trifluoroaniline, SWCNTs, sodium nitrite and chlorosulfonic acid. A capsid assembly modulator that inhibits the replication of hepatitis B virus is synthesised from 3,4,5-trifluoroaniline.
A quasi-2D perovskite film consisting of lead bromide and 3,4,5-trifluoroaniline displays the maximum luminance of 1.2 × 103 cd/m2 and current efficiency up to 0.3 cd/A.
Multiple functional groups
For facile synthesis
Fluorinated aniline building block
For drug discovery, organic synthesis and OLEDs research
Worldwide shipping
Quick and reliable shipping
High purity
>98% High purity
General Information
| CAS Number | 163733-96-8 |
| Chemical Formula | C6H4F3N |
| Full Name | 3,4,5-Trifluoroaniline |
| Molecular Weight | 147.10 g/mol |
| Synonyms | 3,4,5-Trifluorobenzenamine |
| Classification / Family | Fluorinated building block, APIs, Ligands, OLEDs |
Chemical Structure
Product Details
| Purity | 98% |
| Melting Point | Tm = 61 °C – 64 °C |
| Appearance | Grey/purple crystals |
MSDS Documentation
3,4,5-Trifluoroaniline MSDS Sheet
Literature and Reviews
- Ruthenium-catalysed N-alkylation of anilines with primary carbohydrate alcohols via borrowing hydrogen strategy, K. Tsuge et al., Chem. Commun., 59, 7052(2023); DOI: 10.1039/d3cc01931d.
- Detection of ovarian cancer via the spectral fingerprinting of quantum-defect-modified carbon nanotubes in serum by machine learning, M. Kim et al., Nat. Biomed. Eng., 6, 267–275(2022); DOi: 10.1038/s41551-022-00860-y.
- Discovery of a new sulfonamide hepatitis B capsid assembly modulator, H. Na et al., ACS Med. Chem. Lett., 11, 166–171(2022); DOI: 10.1021/acsmedchemlett.9b00550.