Ethyl (4-fluorobenzoyl)acetate

CAS Number 1999-00-4

Chemistry Building Blocks, Fluorinated Building Blocks, Materials, Monomers

Ethyl (4-fluorobenzoyl)acetate CAS 1999-00-4

A fluorinated ketoester derived building block

Used as a ligand in catalytic reaction and synthetic intermediate of pyrimidine for OLEDs, semiconductors and DSSCs

Specifications | MSDS | Literature and Reviews

Ethyl (4-fluorobenzoyl)acetate (p-EFBA), CAS number 1999-00-4, the analogue of β-Ketoester, is typically used as a ligand for improving stereoselectivity of catalytic reactions for great chelating ability to metal centres. Ethyl (4-fluorobenzoyl)acetate is an ideal starting material for synthesizing pyrimidine derivatives via Pinner pyrimidine reaction with amidine/guanidine. The iridium complexes formed by those pyrimidine derivatives are used for long lasting blue phosphorescent organic light-emitting diodes (PhOLEDs). The self-assembled monomer layer of pyrimidine derivatives can engineer the interfacial band of MoS₂ and gold for enhanced device performance in thin film transistors.

Ethyl (4-fluorobenzoyl)acetate can be obtained by the reaction of 4-fluoroacetophenone with diethyl carbonate and sodium hydride as the base in great yield.

Multiple functional groups

For facile synthesis

Worldwide shipping

Quick and reliable shipping

High purity

>97% High purity

Fluorinated phenyloxopropanoate building block

For drug discoveries, dyes, and semiconductors

General Information

CAS Number	1999-00-4
Chemical Formula	C₁₁H₁₁FO₃
Full Name	Ethyl 3-(4-Fluorophenyl)-3-Oxopropanoate
Molecular Weight	210.20 g/mol
Synonyms	(4-Fluorobenzoyl)acetic acid ethyl ester, 3-(4-Fluorophenyl)-3-oxopropionic acid ethyl ester
Classification / Family	Ketoester derivatives, Fluorinated building blocks, Semiconductor synthesis intermediates, Dyes

Chemical Structure

Product Details

Purity	>97%
Boiling Point	T_b = 355 °C – 360 °C at 760 mmHg
Relative Density	1.174 g/mL at 25 °C
Appearance	Slightly yellow liquid

MSDS Documentation

Ethyl (4-fluorobenzoyl)acetate MSDS Sheet

Literature and Reviews

Interfacial band engineering of MoS₂/Gold interfaces using pyrimidine-containing self-assembled monolayers: toward contact-resistance-free bottom-contacts, A. Matković et al., Adv. Electron. Mater., 6, 2000110(2020); DOI: 10.1002/aelm.202000110.
Anomalously long-lasting blue PhOLED feathuring phenyl-pyrimidine cyclomealated iridium emitter, M Sarma et al., Chem, 3, 461–476(2017); DOI: 10.1016/j.chempr.2017.08.001.
Recent progress of pyrimidine derivatives for high-performance organic light-emitting devices, R. Komatsu et al., J. photonics Energy, 8(3), 032108(2018); DOI: 10.1117/1.JPE.8.032108.

Ligand-functionalized Pt nanoparticles as asymmetric heterogeneous catalysts: molecular reaction control by ligand-reactant interactions, A. Šulce et al., Catal. Sci. Technol., 8, 6062-6075(2018); DOI: 10.1039/C8CY01836G.
The long-lasting blues: a new record for phosphorescent organic light-emitting diodes, K. Kirlikovali et al., Chem, 3, 383–389(2017); DOI: 10.1016/j.chempr.2017.08.013.